Targets are organised into protein classes (GPCRs, enzymes, ion channels etc) and then subdivided into families (e.g. Where possible the data are linked to other relevant databases for further information.Įntry points to the data are either via the database search tools (quick search at the top of every page or 'Advanced Search' tools linked from the menu) or through browsing the target and ligand lists. The data are primarily summarised from selected primary literature articles, which are linked to PubMed. The Concise Guide to PHARMACOLOGY replaces GRAC and represents a biennial snap-shot view of the concise family pages from the Guide to PHARMACOLOGY website. (2011) Guide to Receptors and Channels (GRAC), 5th edition. The Guide to Receptors and Channels (GRAC) published in the British Journal of Pharmacology:
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A full contributor list can be viewed here.Ģ. All contributors are attributed near the bottom of the relevant database pages.
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It relies on contributions by expert pharmacologists who volunteer their time. These data constitute the detailed target pages on the GtoPdb site. IUPHAR-DB ( was developed from 2003-2014 under the auspices of NC-IUPHAR (International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug Classification) to provide an accurate educative resource to the scientific community. The information in the Guide to PHARMACOLOGY builds upon two previously available resources:ġ.
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Please refer to this page for details on how to cite the information contained in the Guide to PHARMACOLOGY. If you would like to get in touch with any comments, questions, error reports and suggestions please email us. Specific help pages on the IUPHAR/MMV Guide to Malaria Pharmacology portal and data Contact us Specific help pages on the IUPHAR Guide to Immunopharmacology portal and data (2018) Accessing Expert‐Curated Pharmacological Data in the IUPHAR/BPS Guide to PHARMACOLOGY. These are useful "how-to" guides with illustrations for using the various features:
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TutorialĪ tutorial for using the database and guidance on navigating the website is available to download as a PDF.Ī set of protocols for using the website has been published in Curr Protoc Bioinformatics. Please refer also to the Glossary section of this help page. Terms and symbolsįor further information on the pharmacological terms mentioned see the NC-IUPHAR publication on terms and symbols. This help page describes the terms and symbols used in the database and the search tools available on the website. The Guide to PHARMACOLOGY is based on information previously available separately in the International Union of Basic and Clinical Pharmacology Database (IUPHAR-DB) and the Guide to Receptors and Channels (GRAC). For more information on the Guide to PHARMACOLOGY (abbreviated as GtoPdb) see the About page and the FAQ.